Endocrine Abstracts

Introduction: Pituitary adenomas are benign intracranial tumors. However, some of them are resistant to multiple medical treatments and are clinically considered to be aggressive.Case report: Twenty years old male patient presented with symptomatic hyperglycemia and general weakness. With suspected diagnosis of type 1 diabetes patient was hospitalized in Kauno Klinikos, Endocrinology Department. In further clinical observation acromegalic appearance noti...

Aim: Of the study was to establish normal penile size and testicular volume in healthy Lithuanian newborns.Methods: Of 1204 newborn boys were examined in Panevėžys Hospital due to genitometry. Those with cryptorchidism or hypospadias were excluded. Penis size was measured in 1042 and testicular volume in 712 healthy newborns. The stretched penile length was measured between the pubic ramus and the tip of the glans and the diameter – in...

Endocrinopathies are one of the most common side effects induced by immunotherapy. The side effects result from the activation of immune system, which affects not only cancerous but also healthy body cells. In most cases, only one endocrinopathy occurs, but in our presented case we describe multiple endocrinopathies that occurred to a one person. 53-years-old male patient was referred to the Emergency department due to severe hyperglycemia (37.13 mmol/l) and the following symp...

Introduction: Follicular thyroid carcinoma (FTC) is the second most common thyroid tumor and accounts for about 5-10 % of all thyroid cancers. As FTC often retains the ability to concentrate radioactive iodine (I131), tumor may be responsive to I131 therapy. However, about 60-70 % of all metastatic thyroid cancers are resistant to I131 and has a poor prognosis with 10-year survival rate of 10 % and the average life expectancy 3-5 years after di...

Introduction: 45,X karyotype is known to be related to more severe phenotype disorders, still comparative analysis of the karyotypes and phenotypes in Turner syndrome (TS) is difficult, even in the largest studies, mainly due to differences in patient‘s age and variability in the definition of clinical features (1). We aimed: to assess if monosomia in Turner syndrome patients is related to their cardiometabolic features.Methods: 75 females with conf...

Introduction: Grave’s disease is frequently associated with cytopenia. Pancytopenia, however, is rare. Thyroid hormones have a direct effect on myocardial contractility and left ventricle (LV) diastolic function. Only less than 1% of the patients with hyperthyroidism develop cardiomyopathy with impaired left ventricular systolic function.Case: A 51-year old woman was admitted to the Hospital of Lithuanian University of Health Sciences, Kaunas clinic...

Aim: The aim of this study was to evaluate the influence of age, disease duration, glycaemic control and diabetic nephropathy for the sexual function of women with type 1 diabetes mellitus (T1D).Methods: Study subjects – 18–52 year old women with type 1 diabetes. Participants filled the Female Sexual Function Index (FSFI) and questionnaires about T1D, disease duration, glycaemic control and complications. Laboratory tests including glycated hem...

Objectives: To evaluate sexual function in women with Turner syndrome (TS) in the relation with sex hormones.Methods: The study was undertaken in Lithuanian University of Health Sciences. 65 women with genetically confirmed TS (18–45 years) were enrolled and compared with 65 age-matched healthy controls. Sexual function was evaluated using The Female Sexual Function Index (FSFI). Risk for sexual dysfunction was defined as FSFI score ≤ 26.55. B...

Introduction: Women with Turner syndrome (TS) are known to be at risk of decreased BMD (dBMD). Sex hormone replacement therapy is crucial to ensure the proper BMD formation, although the dBMD remains a problem in TS.Aim: To investigate the prevalence of decreased bone mineralization and it’s association with hormone levels in TS.Subjects: Women with geneticaly confirmed TS aged ≥ 18 year.Methods: T...

Introduction: Aortic dilation (AD) is the life threating complication of Turner syndrome (TS). The reported prevalence of AD in TS various between 12 and 39%. Factors predicting enlargement of diameter of aorta (DA) are still under investigation.Aim: To assess the prevalence of AD in TS in Lithuanian population, to evaluate the possible predictors of AD development.Methods: Forty-three patients with TS aged ≥18 year were enro...